Who has the Best Odds to Win March Madness?
The Duke Blue Devils have the best odds to win March Madness. Here are the current Top 6 March Madness Odds according to FanDuel in North Carolina:
Team | Odds |
---|---|
π Duke | +320 |
π Florida | +380 |
π Auburn | +400 |
π Houston | +600 |
π Alabama | +2200 |
π Tennessee | +2200 |
β Last Updated: | March 20, 2025 |
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Latest Updates Impacting March Madness Odds: March 20, 2025
Last year's March Madness college basketball did not disappoint.
National Championship Storylines:
- Can UConn make it back to the national championship?
- Oddsmakers list Duke as the favorite to win it this season.
- Auburn is also among the favorites to make it to the national championship.
Final Four Storylines:
- Which team will be the surprise of the Final Four this season?
- Houston and Florida are the two favorites, besides Duke and Auburn, to be favorited to make it all the way to the Final Four.
- North Carolina has made the most Final Four appearances in history with 22 but is currently longshots at +10000 to make it.
Elite Eight Storylines:
- Three of four top seeds make it to the Elite Eight every season, giving the top teams a 75% chance of making it.
- N.C. State was the surprise winner in the Elite Eight last season.
- Only two No. 1 seeds appeared in the Elite Eight last season.
Sweet 16 Storylines:
- Only one favorite won on the first day of Sweet 16 matchups: UConn in an 82-52 win over SDSU.
- The Sweet 16 saw No. 1 UNC fall last season to No. 4 Alabama, showcasing one of many upsets.
- Kentucky has made the most Sweet 16 appearances in NCAA history.
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Round of 32 Storylines:
- Eight of eight favorites won outright and went 7-1 against the spread on Day 1.
- Seven underdogs made appearances in the Round of 32 last season.
- New Mexico looks to make it to the Round of 32 for the first time in 13 years.
- UNC and Illinois looked the part with double-digit victories to advance to the Sweet 16.
- If UConn and Duke take care of their Round of 64 showdowns, they will clash for the first time since 1999.
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Round of 64 Storylines:
- Which underdog has the best chance to impact this season's tournament?
- Last year's champion, UConn, will enter the Round of 64 as the No. 8 seed in the East/Raleigh Bracket and will face No. 9 seed Oklahoma.
- Florida, who has +380 odds to win it all, will start the Round of 64 against No. 16 seed Norfolk State.
- Last year's runner-up, Purdue, will enter the Round of 64 as No. 4 in the Midwest/Denver bracket, where it will face No. 13 seed High Point.
- Alabama, which appeared in the Final Four last season, will enter the Round of 64 as the No. 2 seed in the East/Lexington bracket, where it will face No. 15 seed Robert Morris.
- 2022 champion Auburn will start the Round of 64 as the No. 1 seed in the South/Atlanta bracket, attempting to win its second title in four seasons.
- Louisville returns to the NCAA Tournament for the first time in six years, starting as the No. 8 seed against No. 9 Creighton.
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How the UConn Huskies Won 2024 March Madness
UConn's roster was loaded with players who had more tournament experience than any team, and they played with exceptional chemistry.
UConn finished the season ranked 9th in the NCAA in scoring defense, allowing just 63.4 points per game. Coupled with the 23rd-best offensive production, a mix of solid offense and stout defense was a recipe for major success.
At 31-3 on the regular season, the Huskies had long been the favorite to win the East Regionβand the National Championship.
UConn routed Stetson 91-52 in the tournament's first game, handled Northwestern 75-58 to advance to the Sweet 16, crushed Illinois 77-52 in the Elite Eight, and put away Alabama 86-72 in the Final Four.
The defending National Champions were led by head coach Dan Hurley and experienced senior guards Cam Spencer and Tristian Newton, both of whom average over 14 points a game. Three potential first-round NBA draft picks (center Donovan Clingan, guard Stephon Castle, and forward Alex Karaban) brought additional firepower for the Huskies to compete with any team in college basketball.
How To Bet On March Madness
There are a variety of ways to bet on March Madness, including futures and individual game-by-game spreads. You can also bet on teams strictly to make the Final Four and make prop bets.
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March Madness Futures March Madness futures are fun to play because they allow you options to bet on a variety of teams. If you have a few long-shot teams and one or two of them make it to the Sweet 16 or Elite Eight, you have great hedging opportunities. Or you can bet on second-tier contenders, like Marquette and Illinois.
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March Madness Spreads March Madness spreads are exciting because they are available on every game. You are betting on which team will cover the spread, not win the game outright, so even a No. 16 seed has a chance to cover against a No. 1 seed, for example.
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March Madness Props March Madness prop bets allow you to bet on specific things for players in games, such as how many rebounds or points a player will have. You can bet on Purdue's Zach Edey to go over/under 17.5 points, for example. This allows bettors to exploit certain matchups within the game.
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March Madness Bracket Challenges March Madness bracket challenges are a fun way to get a little skin in the game. You select the winner of all 63 games of the tournament before it begins and then get to follow along as the tournament rolls along. If you need suggestions for your March Madness bracket names, we've got you covered.
March Madness Odds FAQ
The Duke Blue Devils have the best odds to win March Madness in 2025. FanDuel lists Duke's 2024-25 odds at +320 to win the NCAA Tournament next season. Translated to implied probability, that gives Duke a 23.8% chance to win it.
The 2025 NCAA men's Final Four will be held at the Alamodome in San Antonio, Texas this season. The University of Texas at San Antonio and the University of Incarnate Word will host the Final Four over two days.
March Madness starts on March 18 with the first play-in games and ends on April 5 with two Final Four games. The tournament truly ends on April 7 at the Alamodome, with the two best teams in college basketball squaring off.
Author

Dan Thompson is a Lead Betting Analyst for BetCarolina.com. Dan's unique experience makes him the perfect fit to find the latest storylines and interesting betting angles impacting Ohio sports betting.