Panthers vs Saints: Odds for Week 15

Panthers vs Saints Odds: Who Is Favored To Win?

Here are the opening odds for the Panthers vs Saints Week 15 matchup. According to DraftKings, Carolina has a 60.8% chance to win, which isn’t surprising given it’s a road game. The Panthers hold a 3–4 record away from home.

🏈 Read up on the Carolina Panthers injury report

Panthers vs Saints Spread: What It Means

The 2.5‑point spread shows that oddsmakers expect the Panthers to win by about a field goal. If you’re betting on Carolina, they’ll need to win by at least 3 points for your ticket to cash. On the flip side, Saints backers would need New Orleans to either win the game or keep the loss within 2 points. I expect Carolina to come out on top, but anything’s possible in a divisional matchup, especially since the Saints won the previous meeting.

Panthers vs Saints Moneyline: What To Know

The Panthers sit at -155 on the moneyline, making them the favorite in their Week 15 matchup against the Saints. That means you’d have to risk more to get a solid payout. Meanwhile, the Saints are at +130, so a $100 bet on New Orleans would win you a total of $230 if they pull off the upset. At those odds, the Saints have a 43.5% chance to win outright.

Panthers Chances To Win vs Saints

Ahead of Week 15, the Panthers got an early Christmas present, the kind of news any playoff-contending team loves in December. All 53 players on Carolina’s active roster were on the field this week, and every player was a full participant in practice. That’s a boost for a team looking to secure a big win on Sunday.

New Orleans has ruled out RB Alvin Kamara and RT Asim Richards, while S Justin Reid is listed as questionable. 

How The Panthers Win vs Saints

For the Panthers to secure a victory, it starts with QB Bryce Young protecting the football and winning the turnover battle. The running game led by Rico Dowdle needs to be effective, Jaycee Horn must deliver a strong performance in the secondary, and the rest of the defense has to play disciplined, sound football throughout the game.

• 📈 Strength: Excellent fourth-down execution.
• 📉 Weakness: Limited star power in the passing game.

How The Saints Win vs Panthers

For the Saints to pull off the upset, they’ll need their defense to control the game, pressuring QB Bryce Young and forcing turnovers to slow Carolina’s offense. On offense, they’ll lean on home-field energy to execute efficiently and sustain drives.

• 📈 Strength: The defense, which forced two turnovers in Week 10 and limited the Panthers to just 175 total yards.
• 📉 Weakness: Despite a strong overall defense, they remain vulnerable against the run.

History of Panthers Saints Games

The Panthers and Saints have played 61 times in the regular season and once in the postseason. The Saints lead the series 33-29. Carolina is 14-17 on the road against New Orleans and 15-16 at home.

All-Time Best Panthers Saints Games

The Saints and Panthers have had some incredible matchups over the last few decades. Here are some of the most memorable contests:

Game 1: 1-7-2018 (2017 NFC Wild Card Round)

The Saints and Panthers met in the 2017 NFL Playoffs for the first time in NFL history. The Saints jumped out to a 21-9 lead going into halftime, and a few late scores by the Panthers allowed them to sneak back into the game. However, the Saints would win 31-26 and would advance to Round 2 of the NFL playoffs.

Game 2: 10-16-2016 (Week 6)

This was one of the highest-scoring games in the rivalry, with 79 total points scored. This was a fantastic matchup between Cam Newton and Drew Brees in their primes, with the Saints getting the 41-38 win. Drew Brees threw for 465 yards and four touchdowns, which was one of his best performances in the NFL.

Game: 10-26-2003 (Week 8)

The Panthers and Saints have not played many overtime games, but this was one to remember in 2003. The Saints scored 17 points in the second quarter to jump out to a 17-10 lead at halftime. But both teams only managed to score field goals in the second half, and it was a 31-yard field goal by John Casey of the Panthers that ultimately ended this game. The Panthers would get the win and advance to 6-1 on the season and would eventually make it to the Super Bowl, losing to the Patriots.

Other Matchups This Season

How Far Will The Panthers Go This Season?

Author

Brandon Justice

@BrandonJustice_

Brandon Justice is a Writer, Commercial Editor, and Fact Checker for BetCarolina.com. He's covered numerous sports betting perspectives for over six years, including everything from analysis & daily picks to reviews & guides. Additionally, he spent six seasons covering college football. The Carolina Panthers follow him on Twitter.